Interactions of Polyoma and Mouse DNAs III. Mechanism of Polyoma Pseudovirion Formation
نویسندگان
چکیده
منابع مشابه
Studies of Mouse Polyoma Virus Infection
The relationship of polyoma (parotid tumor) virus infection to spontaneous and x-ray induced lymphocytic neoplasms (leukemia) in mice has been studied in two sublines of the high leukemic AKR strain, in the high leukemic C58 strain and in the x-ray responsive C3Hf/Bi strain. There was found to be no correlation of hemagglutination-inhibiting (HI) antibody with leukemia appearing at various time...
متن کاملThe epidemiology of mouse polyoma virus infection.
An infectious disease process must be understood at four levels: the level of the agent itself, the level of the interaction of the agent with the individual cell, the level of infection of individual animals, or the pathogenesis of the infection, and at the level of the whole population, or the epi-demiology and ecology of the infection. In this period of intense interest in the nature of the ...
متن کاملFormation and Biologic Role of Polyoma Virus-antibody Complexes
Interaction of polyoma virus, specific antibody, and complement has been studied. Firm evidence has been gathered that C1 through C3 and not C5 through C9 enhance neutralization of virus-antiviral antibody (V-Ab) complexes. C enhancement of neutralization occurs primarily by agglutination of V-Ab complexes and not by virion lysis or attachment of large protein molecules to the V-Ab complex. In ...
متن کاملFormation of nucleoprotein complexes between polyoma empty capsides and DNA.
Purified polyoma empty capsids and polyoma type I DNA interact in a cell-free system to form nucleoprotein complexes. Complexes that consist of one, two, three, and four empty capsids per DNA molecule have been detected. Polyoma virions or capsomers do not react with added DNA to form such complexes.
متن کاملGrowth Properties of Polyoma Virus4nduced
Since the demonstration of the tumor-producing properties of polyoma virus in newborn hamsters by Eddy et al. (7) and Axelrad et a!. (1), it has been shown by Dulbecco and Vogt (4), Sachs (18), and Stoker and MacPherson (921) that the viruscan convert'culturedhamster embryo cells to cells with altered in vitro growth properties and with the capacity to produce tumors when in jected into animals...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1975
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.15.5.1158-1167.1975